Carl D Davis Selected Research

AMG 333

1/2018

Discovery of TRPM8 Antagonist ( S)-6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of Migraine.

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Carl D Davis Research Topics

Disease

4	Migraine Disorders (Migraine) 01/2021 - 01/2008
1	Pain (Aches) 04/2014
1	Neuralgia (Stump Neuralgia) 11/2013
1	Diabetic Neuropathies (Diabetic Neuropathy) 11/2013

Drug/Important Bio-Agent (IBA)

3	Calcitonin Gene-Related PeptideIBA 01/2021 - 01/2008
2	Calcitonin Gene-Related Peptide Receptors (Calcitonin-Gene Related Peptide Receptor)IBA 01/2021 - 08/2008
1	Calcitonin Gene-Related Peptide Receptor AntagonistsIBA 01/2021
1	AMG 333IBA 01/2018
1	AcidsIBA 01/2018
1	CationsIBA 01/2018
1	Formaldehyde (Formol)FDA Link 11/2013
1	4- (8- fluoro- 2- oxo- 1,2- dihydroquinazolin- 3(4H)- yl)- N- (3- (7- methyl- 1H- indazol- 5- yl)- 1- oxo- 1- (4- (piperidin- 1- yl)piperidin- 1- yl)propan- 2- yl)piperidine- 1- carboxamideIBA 08/2008
1	telcagepantIBA 01/2008
1	olcegepantIBA 01/2008

Therapy/Procedure

1	Therapeutics 04/2014